Creatine and resistance training in older adults

Creatine and resistance training in older adults

map-marker.pngThames Hall (baseline and endpoint sessions), Elborn College (exercise classes), Robarts Research Institute (optional MRI)

Older adults are at greater risk for experiencing a reduction in cognitive and physical function. One promising lifestyle intervention to prevent or delay the onset of such declines is exercise, which has been found to improve cognitive function (mental abilities used to perform simple and complex tasks), physical function (muscle mass, bone density) and brain health (structure and function). There is also research demonstrating that creatine, a naturally occurring compound in the body known to decrease with age, can increase muscle mass and bone density in older adults when supplemented. We are interested in examining the effects of creatine supplementation on cognition and brain health in older adults when combined with exercise.

Adults 60+ years old

Healthy volunteers

Exercise 3 times per week

Who can participate in this study?

  • Individuals 60-years-old or older
  • Healthy individuals living independently in the community
  • Normal or corrected-to-normal vision and/or hearing
  • Read, write and speak English fluently
  • Have feelings of memory decline in the past 5 years
  • Being able to exercise at a moderate pace for 60 minutes 3x/week
  • Received clearance from a medical doctor (once deemed eligible) to participate in an exercise program
  • Able to consume a daily supplement containing creatine monohydrate for 26 weeks

What is involved?

This study requires your participation for 26 weeks and you will be asked to adhere to your group assignment, which would involve consuming a daily supplement and attending an exercise class three times per week. You will also attend 2.5-3 hour assessment visits at the beginning of the study (baseline) and after the 26 week intervention (endpoint). An optional MRI brain imaging session is available for participants who are interested.

Principal Investigator & Posting Dates

Principal Investigator: Lindsay Nagamatsu
Study posted on: June 3rd, 2026
Recruitment open

Who can I contact to learn more about this study?

For more information please contact: 

Elias Kekesi: ekekesi@uwo.ca

 

 

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